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Download Manual of Antisense Methodology (Perspectives in Antisense Science) eBook

by Gunther Hartmann,Stefan Endres

Download Manual of Antisense Methodology (Perspectives in Antisense Science) eBook
ISBN:
079238539X
Author:
Gunther Hartmann,Stefan Endres
Category:
Medicine
Language:
English
Publisher:
Springer; 1999 edition (May 31, 1999)
Pages:
205 pages
EPUB book:
1688 kb
FB2 book:
1454 kb
DJVU:
1205 kb
Other formats
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Rating:
4.7
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165


p. c. (perspectives in antisense science). Includes bibliographical references and index. ISBN 978-1-4613-7304-9 ISBN 978-1-4615-5067-9 (eBook).

p. 1. Hartmann, Gunther, 1966-. ll. Endres, Stefan, 1957- ill.

Gunther Hartmann, Stefan Endres.

Perspectives in Antisense Science.

Show all. About the authors. Gunther Hartmann, . is an internist with subspecialties in gastroenterology and intensive care medicine. He is Chief of the Division of Clinical Pharmacology of the medical faculty at the University of Munich. Perspectives in Antisense Science.

oceedings{, title {Manual of Antisense Methodology}, author {Gunther Hartmann and Stefan Endres}, booktitle {Perspectives in Antisense Science}, year {1999} }.

oceedings{, title {Manual of Antisense Methodology}, author {Gunther Hartmann and Stefan Endres}, booktitle {Perspectives in Antisense Science}, year {1999} . Preface G. Hartmann, S. Endres. Part I: The chemistry of antisense oligonucleotides. Chemical synthesis and purification of phosphorothioate antisense oligonucleotides . Sanghvi, et al. 2. How to choose optimal antisense targets in an mRNA B. Schu, H. Brinkmeier. Part II: Antisense application in vitro. 3. How to characterize and improve oligonucleotide uptake into leukocytes M. Bidlingmaier, et al.

Part of the Perspectives in Antisense Science book series (DARE .

While the basic concept of antisense technology is simple, the methodological problems associated with its use are numerous and complex.

Электронная книга "Manual of Antisense Methodology", Gunther Hartmann, Stefan Endres. Эту книгу можно прочитать в Google Play Книгах на компьютере, а также на устройствах Android и iOS. Выделяйте текст, добавляйте закладки и делайте заметки, скачав книгу "Manual of Antisense Methodology" для чтения в офлайн-режиме.

Manual of Antisense Methodology - Perspectives in Antisense Science 4 (Paperback). While the basic concept of antisense technology is simple, the methodological problems associated with its use are numerous and complex.

Restenosis, the proliferation of smooth muscle cells (SMC) that line blood vessels, often follows angioplasty

Bibliographic Details. Restenosis, the proliferation of smooth muscle cells (SMC) that line blood vessels, often follows angioplasty. Despite advances in cardiology, restenosis continues to affect up to 40% of the over 500,000 patients who undergo angioplasty each year.

has been approved for use in the United States. until the late 1980s when advances in several areas provided technical solutions to a number of. impediments.

In the past few years, antisense methodology has moved from in vitro studies to in vivo studies and first human trials. While the basic concept of antisense technology is simple, the methodological problems associated with its use are numerous and complex. Antisense- based methods have proven to be a field of research where careful attention to experimental protocols and appropriate controls is necessary. The Manual of Antisense Methodology emphasizes the application of antisense oligonucleotides, and is a guide for the identification of antisense and non-antisense effects in different experimental settings. The work is organized into three sections: antisense application in vitro, antisense application in vivo (animal models) and finally, clinical antisense studies. Where at all possible, the methods are described in sufficient detail to allow reproduction of a given experiment. The Manual of Antisense Methodology will be of interest to researchers in immunology, cancer research, pharmacology and internal medicine; and physicians conducting clinical studies in these fields.