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Download Ultrastructure of Mast Cells and Basophils (Chemical Immunology and Allergy, Vol. 85) eBook

by A.M. Dvorak,H. Renz

Download Ultrastructure of Mast Cells and Basophils (Chemical Immunology and Allergy, Vol. 85) eBook
ISBN:
3805578644
Author:
A.M. Dvorak,H. Renz
Category:
Medicine & Health Sciences
Language:
English
Publisher:
S. Karger; 1 edition (June 7, 2005)
Pages:
352 pages
EPUB book:
1174 kb
FB2 book:
1821 kb
DJVU:
1540 kb
Other formats
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Rating:
4.9
Votes:
484


These studies include the use of ultrastructural rules that allow identification of basophils and mast cells in new circumstances.

Basophils and mast cells are similar but unique secretory cells which play a central role in inflammatory and immediate allergic reactions. These studies include the use of ultrastructural rules that allow identification of basophils and mast cells in new circumstances. The secretory granules and lipid bodies present in these cells are established as different, important organelles.

Mast Cell Allergy Clin Immunol Human Mast Cell Mucosal Mast Cell Mast Cell Granule. Henderson WR, Kaliner M (1978) Immunologic and non-immunologic generation of superoxide from mast cells and basophils. J Clin Invest 61:187–196PubMedGoogle Scholar. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves. Henderson WR, Kaliner M (1979) Mast cell granules peroxidase; location, secretion, and SRS-A inactivation. J Immunol 122:1322–1328PubMedGoogle Scholar.

Article in Chemical immunology and allergy 62 · April 2015 with 11 Reads

Article in Chemical immunology and allergy 62 · April 2015 with 11 Reads. How we measure 'reads'. Promising results have been shown using mast cell stabilizers, histamine H1 receptor antagonists, selective cysteinyl leukotriene-1 receptor antagonists and inhibitors of 5-lipoxygenase and cyclo-oxygenase.

Mast cells and basophils are the only cells expressing the tetrameric (alphabetagamma2) structure of the high affinity receptor for IgE (FcepsilonRI) and synthesizing histamine in humans. Human FcepsilonRI+ cells are conventionally considered primary effector cells of bronchial asthma.

Given the close proximity of mast cells and nerves to blood vessels in most tissues, they may be considered an important functional unit in neurogenic inflammation. It is becoming apparent that by affecting neuronal functioning, the mast cell and its mediators play an important role in neurogenic inflammation. Mast cells pass information on through afferent nerves to local tissues by axon reflexes and to the spinal cord and thence the brain.

Start by marking Ultrastructure of Mast Cells and Basophils as Want to Read

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Development and distribution of mast cells and neuropeptides in human . International Archives of Allergy and Applied Immunology 80: 44–51.

Development and distribution of mast cells and neuropeptides in human fetus duodenum. World Journal of Gastroenterology, Vol. 10, Issue. The ultrastructure of mast cells from the nine normal inferior turbinates were compared with those found in eight patients with perennial allergic rhinitis due to house dust mite allergy.

Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases Metcalfe DD, Pawankar R, Ackerman SJ, Akin C, Clayton F et al. World Allergy Organization Journal 2016; 9:7. doi: 1. 3 Full Text.

Basophils and mast cells are similar but unique secretory cells which play a central role in inflammatory and immediate allergic reactions. In this book, the author reviews the ultrastructural studies of basophils and mast cells performed since the publication of an earlier monograph in 1991. These studies include the use of ultrastructural rules that allow identification of basophils and mast cells in new circumstances. The secretory granules and lipid bodies present in these cells are established as different, important organelles. A number of standard and newly developed ultrastructural imaging methods are described which define the subcellular locations of chymase, Charcot-Leyden crystal protein, histamine, and heparin as well as materials important in arachidonate and RNA metabolism, and in cytokine biology in basophils and mast cells. The findings presented elucidate new aspects of the secretory mechanisms of basophils and mast cells, their recovery, and the transepithelial route of passage of macromolecules stimulated by permeability mediators released from these cells. Including more than 180 excellent micrographs, this book will be of special interest to basic scientists in immunology, cell biology, secretion and angiogenesis research, and histochemistry. As mast cells and basophils play a crucial role in various diseases, it will be essential reading for allergists, immunologists, dermatologists, hematologists, gastroenterologists, rheumatologists, neurologists, pathologists, pulmonologists, and cardiologists.